Neanderthal Man: In Search of Lost Genomes | 誠品線上

尋找失落的基因組: 尼安德塔人與人類演化史的重建

內容簡介

內容簡介 2022諾貝爾生理學或醫學獎得主Prof. Dr. Svante Pääbo2010年，瑞典遺傳生物學家帕波宣布完成尼安德塔人基因組定序，從此人類演化研究邁入新紀元。在《尼安德塔人》這本書中，帕波描述自己在二十五年漫長的研究中所進行的工作，並敘述為了找出人類和近親尼安德塔人之間遺傳差異，最終獲致的成功，以及期間所付出的極大努力。帕波從1980年代研究埃及木乃伊開始，不斷試驗萃取絕種物種DNA的技術，排除古代DNA汙染問題，建立可靠重建DNA準則，最終使用在重建人類演化史的聖杯上，定出共有三十億個核苷酸序列的尼安德塔人基因組。由於演化人類學及古生物學家對於現代人類起源以及與尼安德塔人的關係，一向頗多爭議，帕波的研究透過基因組的分析，打破許多人對遺傳學真能對人類學有所貢獻的疑慮，解開人類演化之謎。更驚人的是，他發現尼安德塔人並沒有滅絕，所有現代人類體內都帶有尼安德塔人的基因，也就是說，我們都是尼安德塔人的後代。這個發現讓人不得不重新描繪人類演化的歷程。這是一個關於深具遠見的科學家與科學研究本質的故事，對於「我們是誰」這個基本問題，提供了豐富的見解。這也是一本好看的實驗室文學，科學家在探索科學真相時理論上的思辨，不斷檢驗實驗成果，並尋求出路時的波折連連，實驗室成員的互動以及與科學競爭團隊的競合，將科學工作的第一手資料極為生動地記錄下來。本中文書介出自《尋找失落的基因組: 尼安德塔人與人類演化史的重建》八旗文化出版A preeminent geneticist, winner of the 2022 Nobel Prize in medicine, hunts the Neanderthal and Denisovan genomes to answer the biggest question of them all: how did our ancestors become human?Neanderthal Man tells the riveting personal and scientific story of the quest to use ancient DNA to unlock the secrets of human evolution. Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genome in 2010, Neanderthal Man describes the events, intrigues, failures, and triumphs of these scientifically rich years through the lens of the pioneer and inventor of the field of ancient DNA, Svante Pääbo. We learn that Neanderthal genes offer a unique window into the lives of our ancient relatives and may hold the key to unlocking the mysteries of where language came from as well as why humans survived while Neanderthals went extinct.Pääbo redrew our family tree and permanently changed the way we think about who we are and how we got here. For readers of Richard Dawkins, David Reich, and Hope Jahren, Neanderthal Man is the must-read account of how he did it."

作者介紹

作者介紹 Svante PääboSvante Pääbo is the founder of the field of ancient DNA. The director of the department of genetics at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Pääbo has been featured in the New York Times, Newsweek, National Geographic, and the Economist, as well as on NPR, PBS, and BBC. He won the Nobel Prize in Physiology or Medicine in 2022, and in 2009 Time named him one of the 100 Most Influential People in the World. Pääbo lives in Leipzig, Germany.

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